J Exp Clin Cancer Res

期刊全称J Exp Clin Cancer Res
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期刊相关文献 (130)

An immunometabolic prodrug strategy overcomes DHODH inhibitor resistance in refractory melanoma

免疫代谢前药策略克服了难治性黑色素瘤中DHODH抑制剂的耐药性

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03566-6
Yongrui Hai # ，Wenhui Wang # ，Renming Fan # ，Ye Chen # ，Junyan Zhuang ，Shuo Fu ，Guiquan Ding ，Lei Liang ，Junke Song ，Gaofei Wei
发表日期：2025
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Multi-layer stratified oncology platform utilizing transcriptomics, prostate cancer organoids, and modeling of drug response

利用转录组学、前列腺癌类器官和药物反应模型构建的多层分层肿瘤学平台

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03540-2.
Juening Kang # ,Panagiotis Chouvardas # ,Andrew Maalouf ,Daniel Hanhart ,Laura Fernández Cerro ,Wanli Cheng ,Eva Compérat ,Katja Ovchinnikova ,Rahel Etter ,Michaela Medová ,Ulrich Schneeberger ,Beat Roth ,George N Thalmann ,Sofia Karkampouna ,Marianna Kruithof-de Julio
发表日期：2025
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Peripheral nerve injury-induced remodeling of the tumor-associated macrophages promotes immune evasion in breast cancer

周围神经损伤诱导的肿瘤相关巨噬细胞重塑促进乳腺癌的免疫逃逸

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03545-x
Yongxue Jiang # ，Wenfeng Zeng # ，Yaxin Feng # ，Xiaoting Deng # ，Jiayi Wang ，Haiyu Liu ，Boying Gao ，Dexi Bi ，Zifei Liu ，Chaoqun Yang ，Minxia Chen ，Tang Li ，Houying Chen ，Yuxi Zhang ，Luyuan Liang ，Jiannan Xu ，Wen Deng ，Zeyu Yao ，Wei Wu ，Liyan Lao ，Jianing Chen ，Penghan Huang
发表日期：2025
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COX-2/PGE2 axis blockade with celecoxib enhances anti-PD-1 efficacy by activating natural killer cells for residual hepatocellular carcinoma after radiofrequency ablation

塞来昔布阻断COX-2/PGE2轴可通过激活自然杀伤细胞增强抗PD-1疗法对射频消融术后残留肝细胞癌的疗效

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03582-6
Yu Lei # ，Yaowei Bai # ，Xiatong Bai # ，Bo Sun ，Licheng Zhu ，Wenlong Wu ，Yang Su ，Hongsen Zhang ，Yingliang Wang ，Chuansheng Zheng
发表日期：2025
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TEAD3 + high-risk melanoma cells crosstalk with GAS6 + macrophages via the GAS6-TYRO3 ligand-receptor axis to modulate propionate metabolism and drive melanoma progression

TEAD3+高危黑色素瘤细胞通过GAS6-TYRO3配体-受体轴与GAS6+巨噬细胞相互作用，从而调节丙酸代谢并驱动黑色素瘤进展。

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03542-0
Yongjin Fang ，Xiaofan Xu # ，Rihui Lu # ，Ye Huang # ，Xinshen Dai # ，Pucheng Huang # ，Xuefeng Fu # ，Pan Zhuge #
发表日期：2025
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Tumor cells promote immunosuppression in ovarian cancer via a positive feedback loop with MDSCs through the SAA1-IL-1β axis

肿瘤细胞通过SAA1-IL-1β轴与髓源性抑制细胞（MDSC）形成正反馈环路，从而促进卵巢癌中的免疫抑制。

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03536-y
Haoran Hu # ，Meiqin Yang # ，Baoyou Huang # ，Jianyi Ding ，Yashi Zhu ，Xinxin Xu ，Bo Yin ，Huijuan Zhou ，Tiefeng Huang ，Mengjie Li ，Yifan Kou ，Zilale Rahim ，Ang Li ，Wei Wang ，Lingfei Han
发表日期：2025
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Dual CDK and MEK Inhibition potentiates CD8+ T cell-mediated antitumor immunity by inducing pyroptotic cell death in high-mutational head and neck cancer

CDK 和 MEK 双重抑制通过诱导高突变头颈癌细胞发生焦亡，增强 CD8+ T 细胞介导的抗肿瘤免疫。

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03557-7
Fanghui Chen # ，Fang Yang # ，David O Popoola ，Jianqiang Yang ，Chris Tang ，Alexis Payne ，Lynn Zhang ，Nicole C Schmitt ，Jin Xie ，Nabil F Saba ，Yamin Li ，Yong Teng
发表日期：2025
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Detecting actionable mutations from matched plasma-based versus tissue next-generation sequencing in advanced non-small cell lung cancer: a retrospective single centre analysis on site

在晚期非小细胞肺癌中，通过匹配的血浆样本与组织样本的二代测序检测可靶向突变：一项回顾性单中心现场分析

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03480-x
Christophe Bontoux # ,Caroline Lacoux # ,Jonathan Benzaquen ,Jacques Boutros ,Guylène Rignol ,Elodie Long-Mira ,Sandra Lassalle ,Maryline Allegra ,Doriane Bohly ,Mathieu Garcia ,Christelle Bonnetaud ,Olivier Bordone ,Jean-Marc Félix ,Virginie Lespinet-Fabre ,Virginie Tanga ,Charles-Hugo Marquette ,Valérie Taly ,Aurélia Baurès ,Simon Heeke ,Marius Ilié ,Véronique Hofman ,Paul Hofman
发表日期：2025
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Multicenter study correlating molecular characteristics and clinical outcomes of cancer cases with patient-derived organoids

多中心研究将癌症病例的分子特征和临床结果与患者来源的类器官联系起来

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03437-0
Paloma Navarro # ，Tatiana P Grazioso # ，Arantzazu Barquín ，Maria Barba ，Mónica Yagüe ，Carlos Millán ，Irene López ，Elena Sevillano ，Miguel Quiralte ，Paloma Fernández ，Diego Losada ，Eduardo Caleiras ，Julia Calzas ，Beatriz Jiménez ，Sergio Ruiz-Llorente ，Juan Justo ，Félix Guerrero ，Vital Hevia ，Raquel Martín ，Francisco José Pérez-Rodriguez ，Julia Tejerina ，Mario Prieto ，Paula Comune ，Juan Francisco Rodriguez-Moreno ，Jesús García-Donás
发表日期：2025
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CCR8 antagonist suppresses liver cancer progression via turning tumor-infiltrating Tregs into less immunosuppressive phenotype

CCR8拮抗剂通过将肿瘤浸润性Treg细胞转化为免疫抑制作用较弱的表型来抑制肝癌进展

期刊:J Exp Clin Cancer Res
影响因子:11.400
doi:10.1186/s13046-025-03286-x
Binle Tian # ,Zhilong Wang # ,Mei Cao # ,Na Wang # ,Xuebing Jia ,Yuanyuan Zhang ,Jingyi Zhou ,Sijia Liu ,Wen Zhang ,Xiao Dong ,Zheng Li ,Junli Xue ,JianFei Wang ,Guo-Huang Fan ,Qi Li
发表日期：2025
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