Immunohorizons

HIV Nef disrupts Lck signaling by inducing aberrant phosphorylation of its substrates.

Characterization of IgE cross-reactivity and allergenicity of peanut allergens.

花生过敏原的IgE交叉反应性和致敏性特征分析

Single-cell sequencing of human Langerhans cells identifies altered gene expression profiles in patients with atopic dermatitis.

对人类朗格汉斯细胞进行单细胞测序，发现特应性皮炎患者的基因表达谱发生了改变

IL-4 and TGF-β regulate inflammatory cytokines and cellular infiltration in the lung and systemic IL-6 in mouse-adapted SARS-CoV-2 infection.

IL-4 和 TGF-β 调节小鼠适应性 SARS-CoV-2 感染中肺部的炎症细胞因子和细胞浸润以及全身 IL-6

Dynamics of antimicrobial proteins' expression and their bactericidal activity in mouse milk.

小鼠乳汁中抗菌蛋白表达的动态变化及其杀菌活性

Deficiency of interleukin-1 receptor antagonist aggravates Citrobacter rodentium infection in mice.

白细胞介素-1受体拮抗剂缺乏会加重小鼠的鼠柠檬酸杆菌感染

Improved therapeutic efficacy of a bifunctional anti-C5 mAb-FH SCR1-5 fusion protein over anti-C5 mAb in an accelerated mouse model of C3 glomerulopathy.

在加速小鼠 C3 肾小球病模型中，双功能抗 C5 mAb-FH SCR1-5 融合蛋白的治疗效果优于抗 C5 mAb

CD209d/e promotes inflammation and lung injury during influenza virus infection.

CD209d/e 在流感病毒感染期间促进炎症和肺损伤

Deficiency of H3K27 histone demethylase UTX in T cells blunts allergic sensitization and anaphylaxis to peanut.

T 细胞中 H3K27 组蛋白去甲基化酶 UTX 的缺乏会减弱对花生的过敏反应和过敏性休克

Exploring MHC class II I-Ab blockade as a potential treatment for Sjögren's disease in the mouse model.

在小鼠模型中探索 MHC II 类 I-Ab 阻断作为干燥症的潜在治疗方法