Journal of Thrombosis and Haemostasis

Whole blood coagulation in an ex vivo thrombus is sufficient to induce clot neutrophils to adopt a myeloid-derived suppressor cell signature and shed soluble Lox-1

体外血栓中的全血凝固足以诱导凝血中性粒细胞采用髓系抑制细胞特征并脱落可溶性 Lox-1

Mice possess a more limited natural antihuman factor VIII antibody repertoire than humans that is produced disproportionately by marginal zone B cells

与人类相比，小鼠的天然抗人因子 VIII 抗体库更为有限，且主要由边缘区 B 细胞产生

Inhibition of cellular activation induced by platelet factor 4 via the CXCR3 pathway ameliorates Japanese encephalitis and dengue viral infections

通过 CXCR3 通路抑制血小板因子 4 诱导的细胞活化可改善日本脑炎和登革热病毒感染

Thrombin has dual trypsin-like and chymotrypsin-like specificity

凝血酶具有胰蛋白酶样和糜蛋白酶样双重特异性

E3 ubiquitin ligase casitas B-lineage lymphoma-b modulates T-cell anergic resistance via phosphoinositide 3-kinase signaling in patients with immune thrombocytopenia

E3 泛素连接酶 casitas B 系淋巴瘤-b 通过磷酸肌醇 3-激酶信号调节免疫性血小板减少症患者的 T 细胞无能性

Coagulation factor XIII is a critical driver of liver regeneration after partial hepatectomy

凝血因子 XIII 是部分肝切除术后肝脏再生的关键驱动因素

Enhanced venous thrombosis and hypercoagulability in murine and human metabolic dysfunction-associated steatohepatitis.

Pre-existing anti-factor VIII immunity alters therapeutic platelet-targeted factor VIII engraftment following busulfan conditioning through cytotoxic CD8 T cells

在通过细胞毒性 CD8 T 细胞进行白消安调节后，预先存在的抗因子 VIII 免疫会改变治疗性血小板靶向因子 VIII 的植入

Altered cleavage of human factor VIII at the B-domain and acidic region 3 interface enhances expression after gene therapy in hemophilia A mice

人类因子 VIII 在 B 结构域和酸性区域 3 界面处的裂解改变可增强血友病 A 小鼠在基因治疗后的表达

Loss of P2Y1 receptor desensitization does not impact hemostasis or thrombosis despite increased platelet reactivity in vitro

尽管体外血小板反应性增加，但 P2Y1 受体脱敏的丧失不会影响止血或血栓形成