Medchemcomm

Set-up and screening of a fragment library targeting the 14-3-3 protein interface.

Design, synthesis, and in vitro and in vivo characterization of 1-{4-[4-(substituted)piperazin-1-yl]butyl}guanidines and their piperidine analogues as histamine H(3) receptor antagonists.

Novel antimycobacterial C-21 amide derivatives of the antibiotic fusidic acid: synthesis, pharmacological evaluation and rationalization of media-dependent activity using molecular docking studies in the binding site of human serum albumin.

Synthesis and immunogenicity of the Mycobacterium tuberculosis arabinomannan-CRM197 conjugate.

Methoxy substituted 2-benzylidene-1-indanone derivatives as A(1) and/or A(2A) AR antagonists for the potential treatment of neurological conditions.

Aminopyrimidine-galactose hybrids are highly selective galectin-3 inhibitors.

Biochemical and microbiological evaluation of N-aryl urea derivatives against mycobacteria and mycobacterial hydrolases.

Origin and bioactivities of thiosulfinated FK228.

硫代亚磺酸酯化FK228的来源和生物活性

Identification and biological evaluation of novel benzothiazole derivatives bearing a pyridine-semicarbazone moiety as apoptosis inducers via activation of procaspase-3 to caspase-3

鉴定并生物学评价含有吡啶-缩氨基脲部分的新型苯并噻唑衍生物作为凋亡诱导剂，其通过将原胱天蛋白酶-3活化为胱天蛋白酶-3

Toxicities and beneficial protection of H2S donors based on nonsteroidal anti-inflammatory drugs

基于非甾体抗炎药的H2S供体的毒性和有益保护