SRSF2 overexpression induces transcription-/replication-dependent DNA double-strand breaks and interferes with DNA repair pathways to promote lung tumor progression.
SRSF2 过表达诱导转录/复制依赖性 DNA 双链断裂,并干扰 DNA 修复途径,从而促进肺肿瘤进展
期刊:NAR Cancer
影响因子:3.200
doi:10.1093/narcan/zcaf011
Khalife Manal, Jia Tao, Caron Pierre, Shreim Amani, Genoux Aurelie, Cristini Agnese, Pucciarelli Amelie, Leverve Marie, Lepeltier Nina, GarcÃa-RodrÃguez Néstor, Dalonneau Fabien, Ramachandran Shaliny, Fernandez Martinez Lara, Marcion Guillaume, Lemaitre Nicolas, Brambilla Elisabeth, Garrido Carmen, Hammond Ester M, Huertas Pablo, Gazzeri Sylvie, Sordet Olivier, Eymin Beatrice