Neuropharmacology

Decreased voluntary alcohol intake and ventral striatal epigenetic and transcriptional remodeling in male Acss2 KO mice.

Adolescent alcohol exposure disrupts episodic-like memory by impairing dopamine synapses in the mouse prelimbic cortex.

The cannabinoid CB(2) agonist LY2828360 suppresses neuropathic pain behavior and attenuates morphine tolerance and conditioned place preference in rats.

Pharmacological characterization of the novel selective kappa opioid receptor agonists 10-Iodo-Akuammicine and 10-Bromo-akuammicine in mice.

新型选择性 kappa 阿片受体激动剂 10-碘-阿库胺和 10-溴-阿库胺在小鼠体内的药理学特征

Targeting IL-6 as a novel therapeutic approach for alcohol abstinence - related mechanical allodynia.

以IL-6为靶点治疗酒精戒断相关机械性痛觉过敏的新疗法

Striatal GluN2A gene suppression reduces L-DOPA-induced abnormal involuntary movements in parkinsonian rats.

纹状体 GluN2A 基因抑制可减少帕金森病大鼠中左旋多巴诱发的异常不自主运动

Adenosine A(2A) receptor and glial glutamate transporter GLT-1 are synergistic targets to reduce brain hyperexcitability after traumatic brain injury in mice.

腺苷 A(2A) 受体和胶质谷氨酸转运蛋白 GLT-1 是降低小鼠脑外伤后脑过度兴奋性的协同靶点

MRS3997, a dual adenosine A(2A)/A(2B) receptor agonist, reduces brain ischemic damage and alleviates neuroinflammation in rats.

MRS3997 是一种双重腺苷 A(2A)/A(2B) 受体激动剂，可减轻大鼠脑缺血损伤并缓解神经炎症

In vivo calcium extrusion from accumbal astrocytes reduces anxiety-like behaviors but increases compulsive-like responses and compulsive ethanol drinking in mice.

体内伏隔核星形胶质细胞的钙离子外排可减少小鼠的焦虑样行为，但会增加强迫样反应和强迫性饮酒

Age- and cytokine-dependent modulation of GABAergic transmission within the basolateral amygdala of male Sprague Dawley rats.

雄性 Sprague Dawley 大鼠基底外侧杏仁核内 GABA 能传递的年龄和细胞因子依赖性调节