medRxiv

Integrative screening identifies functional variants and VNTRs underlying GWAS signals at the 5p15.33 multi-cancer susceptibility locus.

Early Fc-effector antibody signatures impact COVID-19 disease trajectory.

Integrating multi-omic QTLs and predictive models reveals regulatory architectures at immune related GWAS loci in CD4+ T cells.

Exhausted T cell phenotypes in disseminated coccidioidomycosis.

Intracerebral hemorrhage induces monocyte TNF signaling that is suppressed by Siponimod (BAF312): a single-cell transcriptomics study in patients.

Multimodal single-cell and spatial profiling reveals altered T cell-mediated immunity and B-cell follicular architecture in non-metastatic lymph nodes of patients with aggressive non-small cell lung cancer.

Cooperative Architecture of Mitochondrial Proteome Homeostasis.

线粒体蛋白质组稳态的协同结构。

Identification of serum protein biomarkers in individuals with Niemann-Pick disease, type C1.

尼曼-匹克病 C1 型患者血清蛋白生物标志物的鉴定。

Secreted GPNMB enhances uptake of fibrillar alpha-synuclein in a non-cell-autonomous process that can be blocked by anti-GPNMB antibodies.

分泌型 GPNMB 可增强纤维状 α-突触核蛋白的摄取，这一过程属于非细胞自主过程，可被抗 GPNMB 抗体阻断。

Integrated Biofluid Proteomics Identified Dynamic Functional Biomarkers of LRRK2-Linked Parkinson's Disease Progression.