Global analysis of genes regulated by EvgA of the two-component regulatory system in Escherichia coli.

对大肠杆菌双组分调控系统中 EvgA 调控的基因进行全局分析

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作者:Nishino Kunihiko, Inazumi Yoshihiko, Yamaguchi Akihito
The response regulator EvgA controls expression of multiple genes conferring antibiotic resistance in Escherichia coli (K. Nishino and A. Yamaguchi, J. Bacteriol. 184:2319-2323, 2002). To understand the whole picture of EvgA regulation, DNA macroarray analysis of the effect of EvgA overproduction was performed. EvgA activated genes related to acid resistance, osmotic adaptation, and drug resistance.

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