The associations of circulating 20S proteasomes (c20S) with clinical and serologic disease indices in patients with systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD) are unknown. We present the initial report that c20S levels are elevated in MCTD and correlate with clinically relevant changes in disease activity in SLE and MCTD.
Circulating 20S proteasome levels in patients with mixed connective tissue disease and systemic lupus erythematosus.
混合性结缔组织病和系统性红斑狼疮患者体内循环 20S 蛋白酶体水平
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作者：Majetschak Matthias, Perez Magdalena, Sorell Luis T, Lam Janet, Maldonado Marcos E, Hoffman Robert W
| 期刊： | Clinical and Vaccine Immunology | 影响因子： | 0.000 |
| 时间： | 2008 | 起止号： | 2008 Sep;15(9):1489-93 |
| doi： | 10.1128/CVI.00187-08 | 研究方向： | 免疫/内分泌 |
| 疾病类型： | 红斑狼疮 | ||
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