Hemostatic changes and endothelial activations have been recognized in β-thalassemic patients after matched-donor hematopoietic stem cell transplantation (HSCT) but there are limited studies for haploidentical HSCT. This report demonstrates that the levels of hemostatic and endothelial markers, including thrombin antithrombin complex, prothrombin fragment, D-dimer, von Willebrand factor antigen and thrombomodulin levels, were not significantly different between haploidentical and matched-donor HSCT patients.
No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease.
地中海贫血症中,单倍体相合供体和匹配供体造血干细胞移植在止血和内皮激活方面没有差异
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作者:Lertthammakiat Surapong, Sitthirat Peerasit, Anurathapan Usanarat, Songdej Duantida, Pakakasama Samart, Chuansumrit Ampaiwan, Putawornsub Nattaphat, Sirasittikarn Sawitt, Wantanawijarn Sataporn, Kadegasem Praguywan, Hongeng Suradej, Sirachainan Nongnuch
| 期刊: | Thrombosis Journal | 影响因子: | 2.200 |
| 时间: | 2020 | 起止号: | 2020 Sep 4; 18(1):21 |
| doi: | 10.1186/s12959-020-00232-z | 研究方向: | 发育与干细胞、细胞生物学 |
| 疾病类型: | 贫血 | ||
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