This study indicated that mice immunized with Brucella abortus RB51 bacteria and subsequently challenged with B. abortus 2308 were protected from reinfection. After vaccination, both Th1 and Th2 cytokine patterns were observed. Of those, the early production of gamma interferon seems to have the prominent role in inducing an immunologically based protection.
Mouse cytokine profiles associated with Brucella abortus RB51 vaccination or B. abortus 2308 infection.
与布鲁氏菌RB51疫苗接种或布鲁氏菌2308感染相关的鼠细胞因子谱
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作者：Pasquali P, Adone R, Gasbarre L C, Pistoia C, Ciuchini F
| 期刊： | Infection and Immunity | 影响因子： | 2.800 |
| 时间： | 2001 | 起止号： | 2001 Oct;69(10):6541-4 |
| doi： | 10.1128/IAI.69.10.6541-6544.2001 | 种属： | Mouse |
| 研究方向： | 细胞生物学 | ||
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