We evaluated the anti-accelerated epidermal skin aging effects of compound K (CK) on keratinocytes using IL-17A and ultraviolet B. CK restored epidermal functions and reduced the induction of pro-inflammatory cytokines by inhibiting NF-κB and p38 MAPK activation. CK plays a significant role in controlling accelerated epidermal skin aging.
Compound K suppresses epidermal aging induced by IL-17A treatment and UVB irradiation.
化合物 K 可抑制 IL-17A 处理和 UVB 照射引起的表皮老化
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作者:Kim A Young, Jung Ji-Yong, Kim Donghyun, Cho Jeong Hun, Hong Yong Deog, Kim Hyoung-June, Cho Si-Young
| 期刊: | Journal of Ginseng Research | 影响因子: | 5.600 |
| 时间: | 2025 | 起止号: | 2025 May;49(3):326-330 |
| doi: | 10.1016/j.jgr.2025.03.004 | 靶点: | IL-17 |
| 研究方向: | 信号转导 | ||
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