Conventional wound closure techniques, such as suturing and stapling, often cause infection, delayed healing, and tissue damage, particularly in fragile or compromised tissues. A sutureless, battery-free adhesive strip (SBF strip) is developed to integrate shape-memory-assisted mechanical approximation with impedance-matched electrical stimulation for enhanced tissue repair. The device incorporates a shape memory polymer (SMP) responsive at near-body temperature and a robust wet-adhesive interface (> 200âJâm(-2)), enabling rapid attachment and uniform closure under mild heating (40â°C). A built-in ultrasound-driven triboelectric system achieves optimal skin-impedance matching (~50âkΩ), generating electric fields up to 0.59âkVâm(-1) under 0.5âWâcm(-2) to promote cellular migration and proliferation. Finite element simulations reveal that SMP-induced contraction redistributes local mechanical strain, reducing scarring. In vivo rat studies demonstrate a 61.7% reduction in scar area compared to sutures, along with improved epithelial regeneration, collagen deposition, and angiogenesis. This mechanically and electrically synergistic platform offers a scalable, battery-free wound therapy strategy, reducing dependence on external power and disposable components while enabling precision-guided healing.
Self-contracting, battery-free triboelectric wound healing strip with strong wet adhesion.
自收缩、无电池摩擦电伤口愈合贴片,具有很强的湿粘附性
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作者:Meng Xiangchun, Xiao Xiao, Jeon Sera, Cho Daniel Sanghyun, Zhang Kejia, Kwon Yong Hyun, Mo Hyeon, Park Yoojin, Park Byung-Joon, Kim Dabin, Pang Fengyi, Kim SeongMin, Choi Byung-Ok, Dai Keren, Kim Sang-Woo
| 期刊: | Nature Communications | 影响因子: | 15.700 |
| 时间: | 2025 | 起止号: | 2025 Aug 5; 16(1):7220 |
| doi: | 10.1038/s41467-025-62312-w | ||
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