Real-time PCR as a prognostic tool for human congenital toxoplasmosis
实时 PCR 作为人类先天性弓形虫病的预后工具
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作者：Júlia Gatti Ladeia Costa, Ana Carolina Aguiar Vasconcelos Carneiro, Alice Thomáz Tavares, Gláucia Manzan Queiroz Andrade, Daniel Vitor Vasconcelos-Santos, José Nélio Januário, Daniel Menezes-Souza, Ricardo Toshio Fujiwara, Ricardo Wagner Almeida Vitor
Abstract
Real-time PCR (qPCR) was positive in 72/150 (48%) blood samples of newborns with congenital toxoplasmosis. Among infants with active retinochoroiditis, 68% had positive qPCR results, while positivity was 29% (P=0.009) in the absence of ocular involvement. Positive qPCR was associated with the presence of retinochoroidal lesions, with an odds ratio of 2.8.
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