Evaluation of Chitosan and Cellulosic Polymers as Binding Adsorbent Materials to Prevent Aflatoxin B1, Fumonisin B1, Ochratoxin, Trichothecene, Deoxynivalenol, and Zearalenone Mycotoxicoses Through an In Vitro Gastrointestinal Model for Poultry

通过家禽体外胃肠道模型评估壳聚糖和纤维素聚合物作为结合吸附材料预防黄曲霉毒素 B1、伏马毒素 B1、赭曲霉毒素、单端孢霉烯、脱氧雪腐镰刀菌烯醇和玉米赤霉烯酮霉菌毒素中毒的效果

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作者:Bruno Solís-Cruz, Daniel Hernández-Patlán, Eric Beyssac, Juan D Latorre, Xochitl Hernandez-Velasco, Ruben Merino-Guzman, Guillermo Tellez, Raquel López-Arellano

Abstract

Mycotoxins are secondary toxic metabolites that are produced by fungi representing threats to human and animal health. The objective of this study was to evaluate the adsorption capacity of Chitosan (CHI), and three cellulosic polymers (HPMC, CMC, and MCC), on six mycotoxins (AFB&sub1;; FUB&sub1;; OTA; T-2; DON; and, ZEA) using an in vitro digestive model for poultry. The adsorbent capacity of the materials in the supernatant of each compartment was evaluated by a non-competitive chemiluminescent assay. Control groups with no adsorbent material had an adsorption value of 0.00% against all six mycotoxins that were evaluated. All four materials tested showed significant (p < 0.05) binding activity against all of the mycotoxins when compared with the control non-treated group. However HPMC, CMC, and MCC showed better adsorbent capacity when compared with CHI.

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