Accurate, noninvasive detection of Helicobacter pylori DNA from stool samples: potential usefulness for monitoring treatment

准确、无创地检测粪便样本中的幽门螺杆菌 DNA:对监测治疗有潜在用途

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作者:Anthony P Shuber, Jennifer J Ascaño, Kevin A Boynton, Anastasia Mitchell, Henry F Frierson Jr, Wa'el El-Rifai, Steven M Powell

Abstract

A novel DNA assay demonstrating sensitive and accurate detection of Helicobacter pylori from stool samples is reported. Moreover, in three individuals tested for therapeutic response, the assay showed the disappearance of H. pylori DNA during treatment. Thus, this noninvasive molecular biology-based assay has the potential to be a powerful diagnostic tool given its ability to specifically identify H. pylori DNA.

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