A safe and effective vaccine candidate is urgently needed for the ongoing COVID-19 pandemic, caused by SARS-CoV-2. Here we report that recombinant SARS-CoV-2 RBD protein immunization in mice is able to elicit a strong antibody response and potent neutralizing capability as measured using live or pseudotyped SARS-CoV-2 neutralization assays.
Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain.
SARS-CoV-2 受体结合域诱导的中和抗体反应
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作者:Huang Ping-Han, Tsai Hsiao-Han, Liao Bo-Hung, Lin Yi-Ling, Jan Jia-Tsrong, Tao Mi-Hua, Chou Yu-Chi, Hu Che-Ming Jack, Chen Hui-Wen
| 期刊: | Human Vaccines & Immunotherapeutics | 影响因子: | 3.500 |
| 时间: | 2021 | 起止号: | 2021 Mar 4; 17(3):654-655 |
| doi: | 10.1080/21645515.2020.1814098 | 研究方向: | 炎症/感染 |
| 疾病类型: | 新冠 | ||
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