Synthesis, crystal structure and in vitro anti-proliferative activity of 2-[(4-acetyl-phen-yl)carbamo-yl]phenyl acetate.

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作者:Mohamed-Ezzat Reham A, Kariuki Benson M, Srour Aladdin M
2-[(4-Acetyl-phen-yl)carbamo-yl]phenyl acetate, C(17)H(15)NO(4), has been synthesized and structurally characterized. In the structure, N-H⋯O hydrogen-bonding inter-actions form chains of mol-ecules aligned along the [101] direction. The chains are linked by π-π and C-H⋯π inter-actions, forming a three dimensional network. The compound has been screened for in vitro anti-proliferative activity revealing considerable activity.

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