Risk Factors Affecting the Infusion Rate of Chemotherapeutic Agents within 2 Hours after Preparation and the Intervention Effect of the Quality Control Circle.

OBJECTIVE: To investigate the risk factors for the infusion rate of chemotherapeutic agents within 2 hours after preparation and to observe the application effect of the quality control circle. METHODS: The infusion rates of chemotherapeutic agents within 2 hours after the preparation in different wards of our hospital in February 2019 were counted and relevant factors were collected. Binary logistic regression analysis was utilized to screen the risk factors for the infusion rate of chemotherapeutic agents within 2 hours after the preparation. In March 2019, the quality control circle intervention was implemented according to risk factors. The application effect of the quality control circle was observed. RESULTS: Logistic regression analysis results exhibited that insufficient attention to key performance indicator (KPI), heavy workload, forgotten or unfamiliar KPI, no real-time attention by the head of the department, simultaneous preparation of multiple groups of infusions for the same patient, preparation of all chemotherapeutic agents in the morning, and self-prepared medicine without a medical order were independent risk factors for infusion of chemotherapeutic agents beyond 2 hours after preparation (P < 0.05). The infusion rate of the chemotherapeutic agents (96.54%) within 2 hours after the preparation was significantly higher after the application of the quality control circle than that before the application (60.45%). The improvement rate was 59.65% and the goal achievement rate was 104.37% (P < 0.01). CONCLUSION: Insufficient attention to KPI, heavy workload, forgotten or unfamiliar KPI, no real-time attention by the head of the department, simultaneous preparation of multiple groups of infusions for the same patient, preparation of all chemotherapeutic agents in the morning, and self-prepared medicine without a medical order are crucial risk factors for limiting the increase in the infusion rate of chemotherapeutic agents within 2 hours after the preparation. Quality control circle intervention based on risk factors can effectively improve the infusion rate of chemotherapeutic agents within 2 hours after the preparation.