Clostridioides difficile causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen.
A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile.
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作者：Rosas-Lemus Monica, Dey Supratim, Minasov George, Tan Kemin, Anderson Spencer M, Brunzelle Joseph, Nocadello Salvatore, Shabalin Ivan, Filippova Ekaterina, Halavaty Andrei, Kim Youngchang, Maltseva Natalia, Osipiuk Jerzy, Minor Wladek, Joachimiak Andrzej, Savchenko Alexei, Anderson Wayne F, Satchell Karla J F
| 期刊： | Microbiology Resource Announcements | 影响因子： | 0.600 |
| 时间： | 2023 | 起止号： | 2023 Oct 19; 12(10):e0050723 |
| doi： | 10.1128/MRA.00507-23 | ||
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