3-(4-Amino-phen-yl)-5-(4-meth-oxy-phen-yl)-4,5-di-hydro-1H-pyrazole-1-carbo-thio-amide.

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作者:Suwunwong Thitipone, Chantrapromma Suchada, Chidan Kumar C S, Fun Hoong-Kun
In the mol-ecule of title pyrazoline derivative, C17H18N4OS, the pyrazole ring adopts an envelope conformation with the flap atom, which bears the meth-oxy-phenyl substituent, displaced by 0.0750†(12)†à from the plane through the other ring atoms. The two substituted benzene rings make a dihedral angle of 70.59†(6)°. The meth-oxy group is twisted slightly with respect to the attached benzene ring [Cmeth-yl-O-C-C torsion angle = -8.84†(15)°]. An intra-molecular N-H⋯N hydrogen bond occurs. In the crystal, the pyrazoline mol-ecules are linked by N-H⋯O and N-H⋯S hydrogen bonds into zigzag layers parallel to the bc plane and stacked along the a axis by π-π inter-actions with centroid-centroid distances of 3.4690†(7) and 3.5792†(7)†à . C-H⋯π inter-actions are also present.

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