The title compound, C(32)H(23)ClN(2)O(4), has a quinoline, a chloro-phenyl and an acenaphthalene ring system attached to a central pyrrolidine ring, which has three stereogenic centers. Nevertheless, the compound crystallizes as a racemate with two mol-ecules of identical chirality in the asymmetric unit. They differ in the conformation of the five-membered pyrrolidine ring; in one molecule it has an envelope conformation, while in the other molecule it has a twisted conformation. In each molecule there is an intra-molecular O-Hâ¯O hydrogen bond making an S(6) ring motif. In the crystal, pairs of N-Hâ¯O hydrogen bonds produce inversion dimers with R(2) (2)(8) motifs. There are also C-Hâ¯O interactions present. The crystal structure contains voids (60â à (3)) within which there is no evidence of solvent mol-ecules.
(1R*,3'S*,4'R*)-4'-(4-Chloro-phen-yl)-3'-[(4-hy-droxy-2-oxo-1,2-dihydro-quinolin-3-yl)carbon-yl]-1'-methyl-spiro-[ace-naphthyl-ene-1,2'-pyrrolidin]-2-one.
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作者:Vennila K N, Sankaran M, Mohan P S, Velmurugan D
| 期刊: | Acta Crystallographica Section E-Structure Reports Online | 影响因子: | 0.600 |
| 时间: | 2011 | 起止号: | 2011 Dec 1; 67(Pt 12):o3376-7 |
| doi: | 10.1107/S1600536811048896 | ||
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