In the title compound, C(13)H(12)ClN(5), which is a derivative of the anti-tumor agent pazopanib {systematic name: 5-[[4-[(2,3-di-methyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrim-idine fragments form a dihedral angle of 62.63â (5)°. In the crystal, pairs of mol-ecules related by twofold rotational symmetry are linked into dimers through Ï-Ï inter-actions between the indazole ring systems [centroid-centroid distance = 3.720â (2)â à ]. Weak inter-molecular C-Hâ¯N hydrogen bonds further assemble these dimers into columns propagated in [001].
N-(2-Chloro-pyrimidin-4-yl)-N,2-di-methyl-2H-indazol-6-amine.
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作者:Qi Hao-Fei, Liu Bing-Ni, Liu Mo, Liu Deng-Ke
| 期刊: | Acta Crystallographica Section E-Structure Reports Online | 影响因子: | 0.600 |
| 时间: | 2010 | 起止号: | 2010 Oct 30; 66(Pt 11):o2955 |
| doi: | 10.1107/S1600536810042753 | ||
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