Development and validation of real-time recombinase polymerase amplification-based assays for detecting HPV16 and HPV18 DNA

基于实时重组酶聚合酶扩增的检测 HPV16 和 HPV18 DNA 的检测方法的开发和验证

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作者:Jiaxu Ying, Lingjing Mao, Yujing Tang, Meriem Fassatoui, Wei Song, Xiaosheng Xu, Xiaojian Tang, Jing Li, Hua Liu, Fangfang Jian, Qinwen Du, Gary Wong, Weiwei Feng, Nicolas Berthet

Abstract

HPV DNA screening is an effective approach for the prevention of cervical cancer. The novel real-time recombinase polymerase amplification-based HPV detection systems we developed constitute an improvement over the HPV detection methods currently used in clinical practice and should help to extend cervical cancer screening in the future, particularly in point-of-care test settings.

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