Transmission dynamics of brucellosis: Mathematical modelling and applications in China.

Brucellosis, the most common zoonotic disease worldwide, represents a great threat to animal husbandry with the potential to cause enormous economic losses. Meanwhile, brucellosis is one of the major public-health problems in China, and the number of human brucellosis cases has increased dramatically in recent years. In order to show the main features of brucellosis transmission in China, we give a systematic review on the transmission dynamics of brucellosis including a series of mathematical models and their applications in China. For different situations, dynamical models of brucellosis transmission in single population and multiple populations are devised based on ordinary differential equations. Furthermore, we revealed the spatial-temporal characteristics and effective control measures of brucellosis transmission. The results may provide new perspectives for the prevention and control of other types of zoonoses.