Postantibiotic effects (PAEs) of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis ATCC 27294 were studied using a radiometric culture system. Rifapentine at 20 mg/liter gave the longest PAE (104 h) among the drugs used alone. The combinations of rifapentine plus isoniazid, rifapentine plus moxifloxacin, and isoniazid plus moxifloxacin gave PAEs of 136.5, 59.0, and 8.3 h, respectively.
In vitro postantibiotic effects of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis.
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作者:Chan Chiu-Yeung, Au-Yeang Carrie, Yew Wing-Wai, Leung Chi-Chiu, Cheng Augustine F B
| 期刊: | Antimicrobial Agents and Chemotherapy | 影响因子: | 4.500 |
| 时间: | 2004 | 起止号: | 2004 Jan;48(1):340-3 |
| doi: | 10.1128/AAC.48.1.340-343.2004 | ||
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