We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant.
Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
马来西亚产生 IMP-7 β-内酰胺酶的耐碳青霉烯类铜绿假单胞菌
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作者:Ho Siaw Eng, Subramaniam Geetha, Palasubramaniam Selvi, Navaratnam Parasakthi
| 期刊: | Antimicrobial Agents and Chemotherapy | 影响因子: | 4.500 |
| 时间: | 2002 | 起止号: | 2002 Oct;46(10):3286-7 |
| doi: | 10.1128/AAC.46.10.3286-3287.2002 | 研究方向: | 微生物学 |
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