Fibrils of the protein α-synuclein (Asyn) are implicated in the pathogenesis of Parkinson Disease, Lewy Body Dementia, and Multiple System Atrophy. Numerous forms of Asyn fibrils have been studied by solid-state NMR and resonance assignments have been reported. Here, we report a new set of (13)C, (15)N assignments that are unique to fibrils obtained by amplification from postmortem brain tissue of a patient diagnosed with Lewy Body Dementia.
(13)C and (15)N resonance assignments of alpha synuclein fibrils amplified from Lewy Body Dementia tissue.
从路易体痴呆组织中扩增的α-突触核蛋白原纤维的（13）C和（15）N共振归属
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作者：Barclay Alexander M, Dhavale Dhruva D, Borcik Collin G, Milchberg Moses H, Kotzbauer Paul T, Rienstra Chad M
| 期刊： | Biomolecular Nmr Assignments | 影响因子： | 0.600 |
| 时间： | 2023 | 起止号： | 2023 Dec;17(2):281-286 |
| doi： | 10.1007/s12104-023-10156-0 | 研究方向： | 免疫/内分泌 |
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