The title compound, C(18)H(18)F(2)N(2)O(3), crystallizes with two independent mol-ecules (A and B) in the asymmetric unit. They differ essentially in the orientation of the pyridine ring with respect to the benzene ring; these two rings are inclined to each other by 53.3â (2)° in mol-ecule A and by 72.9â (2)° in mol-ecule B. The 3-(cyclo-propyl-meth-oxy) side chain has an extended conformation in both mol-ecules. The two mol-ecules are linked by a pair of C-Hâ¯O hydrogen bonds and two C-Hâ¯Ï inter-actions, forming an A-B unit. In the crystal, this unit is linked by N-Hâ¯O hydrogen bonds, forming a zigzag -A-B-A-B- chain along [001]. The chains are linked by C-Hâ¯N and C-Hâ¯F hydrogen bonds to form layers parallel to the ac plane. Finally, the layers are linked by a third C-Hâ¯Ï inter-action, forming a three-dimensional structure. The major contributions to the Hirshfeld surface are those due to Hâ¯H contacts (39.7%), followed by Fâ¯H/Hâ¯F contacts (19.2%).
Crystal structure and Hirshfeld surface analysis of 3-(cyclo-propyl-meth-oxy)-4-(di-fluoro-meth-oxy)-N-(pyridin-2-ylmeth-yl)benzamide.
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作者:Artheswari G, Maheshwaran V, Gautham N
| 期刊: | Acta Crystallographica Section E: Crystallographic Communications | 影响因子: | 0.500 |
| 时间: | 2019 | 起止号: | 2019 Sep 20; 75(Pt 10):1515-1518 |
| doi: | 10.1107/S2056989019012866 | ||
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