Synthesis, structure, catalytic and cytotoxic activities of chlorido-(5-nitro-quinolin-8-olato-κ(2) N,O)(tri-cyclo-hexyl-phosphine-κP)platinum(II).

The title complex, [Pt(C(10)H(5)N(2)O(3))Cl(C(18)H(33)P)], was synthesized by the reaction of [PtCl(C(10)H(5)N(2)O(3))(η(2)-C(2)H(4))] and PCy(3) at room temperature for 2†h with a yield of 80%. The deprotonated 5-nitro-quinoline-8-ol (C(10)H(5)N(2)O(3) (-)) anion coordinates to the metal atom in a bidentate mode via its N and O atoms with a N-Pt-O bite angle of 80.0†(3)°. The tri-cyclo-hexyl-phosphine P atom is in a trans position with respect to the N atom in the square-planar coordination environment of the metal atom. The packing features zigzag chains linked by C-H⋯O inter-actions and continuous channels occupied by disordered solvent mol-ecules, both running in the a-axis direction. The complex shows weak activity against four cancer cell lines with IC(50) values > 120†µM, but significant catalytic ability and selectivity for hydro-silylation between phenyl-acetyl-ene and tri-ethyl-silane.