Crystal structure and Hirshfeld surface analysis of ethyl 2-[5-(3-chloro-benz-yl)-6-oxo-3-phenyl-1,6-di-hydro-pyridazin-1-yl]acetate.

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作者:El Kalai Fouad, Baydere Cemile, Daoui Said, Saddik Rafik, Dege Necmi, Karrouchi Khalid, Benchat Noureddine
The title pyridazinone derivative, C(21)H(19)ClN(2)O(3), is not planar. The unsubstituted phenyl ring and the pyridazine ring are inclined to each other, making a dihedral angle of 17.41†(13)° whereas the Cl-substituted phenyl ring is nearly orthogonal to the pyridazine ring [88.19†(13)°]. In the crystal, C-H⋯O hydrogen bonds generate dimers with R (2) (2)(10) and R (2) (2)(24) ring motifs which are linked by C-H⋯O inter-actions, forming chains extending parallel to the c-axis direction. The inter-molecular inter-actions were investigated using Hirshfeld surface analysis and two-dimensional fingerprint plots, revealing that the most significant contributions to the crystal packing are from H⋯H (44.5%), C⋯H/H⋯C (18.5%), H⋯O/H⋯O (15.6%), Cl⋯H/H⋯Cl (10.6%) and C⋯C (2.8%) contacts.

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