There is an unmet need for effective ovarian cancer screening and diagnostic approaches that enable earlier-stage cancer detection and increased overall survival. We have developed a high-performing accessible approach that evaluates cfDNA fragmentomes and protein biomarkers to detect ovarian cancer.
Early Detection of Ovarian Cancer Using Cell-Free DNA Fragmentomes and Protein Biomarkers.
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作者：Medina Jamie E, Annapragada Akshaya V, Lof Pien, Short Sarah, Bartolomucci Adrianna L, Mathios Dimitrios, Koul Shashikant, Niknafs Noushin, Noë Michaël, Foda Zachariah H, Bruhm Daniel C, Hruban Carolyn, Vulpescu Nicholas A, Jung Euihye, Dua Renu, Canzoniero Jenna V, Cristiano Stephen, Adleff Vilmos, Symecko Heather, van den Broek Daan, Sokoll Lori J, Baylin Stephen B, Press Michael F, Slamon Dennis J, Konecny Gottfried E, Therkildsen Christina, Carvalho Beatriz, Meijer Gerrit A, Andersen Claus Lindbjerg, Domchek Susan M, Drapkin Ronny, Scharpf Robert B, Phallen Jillian, Lok Christine A R, Velculescu Victor E
| 期刊： | Cancer Discovery | 影响因子： | 33.300 |
| 时间： | 2025 | 起止号： | 2025 Jan 13; 15(1):105-118 |
| doi： | 10.1158/2159-8290.CD-24-0393 | ||
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