Co-delivery of sorafenib and an FSP1 inhibitor triggers dual ferroptosis in tumor cells and immunosuppressive macrophages for enhanced immunotherapy in mouse models of hepatocellular carcinoma

在肝细胞癌小鼠模型中，索拉非尼与FSP1抑制剂联合递送可诱导肿瘤细胞和免疫抑制性巨噬细胞发生双重铁死亡，从而增强免疫治疗效果。