Two distinct forms of Factor VIII coagulant protein in human plasma. Cleavage by thrombin, and differences in coagulant activity and association with von Willebrand factor

人血浆中存在两种不同的凝血因子VIII蛋白。它们可被凝血酶切割，且在凝血活性和与血管性血友病因子（von Willebrand factor）的结合方面存在差异。