Tuning cell adhesive properties via layer-by-layer assembly of chitosan and alginate

通过壳聚糖和海藻酸盐的逐层组装来调节细胞粘附特性

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作者:Joana M Silva, José R García, Rui L Reis, Andrés J García, João F Mano

Significance

Multilayered films based on marine-derived polysaccharides were obtained by layer-by-layer (LbL). Biological tests with human umbilical vein endothelial cells (HUVECs) showed the potential of these films to tailor cell adhesion, spreading and proliferation. These multilayered films promise to be versatile and tunable model of cell adhesive and non-adhesive films.

Statement of significance

Multilayered films based on marine-derived polysaccharides were obtained by layer-by-layer (LbL). Biological tests with human umbilical vein endothelial cells (HUVECs) showed the potential of these films to tailor cell adhesion, spreading and proliferation. These multilayered films promise to be versatile and tunable model of cell adhesive and non-adhesive films.

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