SGC-CAMKK2-1: A Chemical Probe for CAMKK2
SGC-CAMKK2-1：CAMKK2 的化学探针
阅读：3
作者：Carrow Wells，Yi Liang，Thomas L Pulliam，Chenchu Lin，Dominik Awad，Benjamin Eduful，Sean O'Byrne，Mohammad Anwar Hossain，Carolina Moura Costa Catta-Preta，Priscila Zonzini Ramos，Opher Gileadi，Carina Gileadi，Rafael M Couñago，Brittany Stork，Christopher G Langendorf，Kevin Nay，Jonathan S Oakhill，Debarati Mukherjee，Luigi Racioppi，Anthony R Means，Brian York，Donald P McDonnell，John W Scott ，Daniel E Frigo ，David H Drewry
| 期刊： | Cells | 影响因子： | 5.100 |
| 时间： | 2023 | 起止号： | 2023 Jan 11;12(2):287. |
| doi： | PMC9856672 |
Abstract
The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes. Despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed. Having a selective small molecule tool to interrogate this kinase will help demonstrate that CAMKK2 inhibition can be therapeutically beneficial. Herein, we disclose SGC-CAMKK2-1, a selective chemical probe that targets CAMKK2.
特别声明
1、本页面内容包含部分的内容是基于公开信息的合理引用；引用内容仅为补充信息，不代表本站立场。
2、若认为本页面引用内容涉及侵权，请及时与本站联系，我们将第一时间处理。
3、其他媒体/个人如需使用本页面原创内容，需注明“来源：[生知库]”并获得授权；使用引用内容的，需自行联系原作者获得许可。
4、投稿及合作请联系：info@biocloudy.com。
