Comparative single-cell and spatial profiling of anti-SSA-positive and anti-centromere-positive Sjögren's disease reveals common and distinct immune activation and fibroblast-mediated inflammation

对抗SSA阳性和抗着丝粒阳性干燥综合征患者进行单细胞和空间分析，揭示了二者共同和独特的免疫激活以及成纤维细胞介导的炎症反应。