Three neoplasms in a Eurasian otter (Lutra lutra): malignant melanoma, trichoblastoma and mammary gland adenoma

欧亚水獭(Lutra lutra)的三种肿瘤:恶性黑色素瘤、毛母细胞瘤和乳腺腺瘤

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作者:Naoyuki Fuke, Nguyen Van Diep, Takuya Hirai, Mathurot Suwanruengsri, Uda Zahli Izzati, Ryoji Yamaguchi

Abstract

An eighteen-year-old female Eurasian otter became emaciated and died. Necropsy examination revealed nose and thoracic cutaneous masses, abdominal subcutaneous mass, and multiple nodules in the liver and lungs. Malignant melanoma was found in the nose cutaneous mass and to have metastasized to the liver, lungs, kidneys, adrenal glands, mammary glands and left mandibular lymph node. The neoplastic cells were labeled for vimentin, melanoma, and S100. The cutaneous mass in the thoracic area consisted of spindle shaped neoplastic epithelial cells and was diagnosed as trichoblastoma. Mammary gland adenoma was observed in the abdominal subcutaneous mass. This is the first report of primary three neoplasms of malignant melanoma, trichoblastoma and mammary gland adenoma in a Eurasian otter.

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