Abaloparatide and paclitaxel combination therapy Improves bone volume and tumor burden in Bone-Metastatic breast cancer.

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作者:Miller Jade S, Kane Jeremy F, Ward Patricia A, Shawkey Marvel, Watkins Adaline, Johnson Rachelle W, Rhoades Julie A
•Abaloparatide is FDA-approved for osteoporosis but is not well characterized in patients with bone metastases.•Combination abaloparatide and paclitaxel reduced tumor and increased bone volume in an intratibial model of cancer in bone.•Abaloparatide alone did not impact tumor burden or bone volume in tumor limb.

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