The Porosity Design and Deformation Behavior Analysis of Additively Manufactured Bone Scaffolds through Finite Element Modelling and Mechanical Property Investigations

通过有限元建模和机械性能研究对增材制造骨支架的孔隙率设计和变形行为进行分析

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作者:Shummaila Rasheed, Waqas Akbar Lughmani, Muhammad Mahabat Khan, Dermot Brabazon, Muhannad Ahmed Obeidi, Inam Ul Ahad

Abstract

Additively manufactured synthetic bone scaffolds have emerged as promising candidates for the replacement and regeneration of damaged and diseased bones. By employing optimal pore architecture, including pore morphology, sizes, and porosities, 3D-printed scaffolds can closely mimic the mechanical properties of natural bone and withstand external loads. This study aims to investigate the deformation pattern exhibited by polymeric bone scaffolds fabricated using the PolyJet (PJ) 3D printing technique. Cubic and hexagonal closed-packed uniform scaffolds with porosities of 30%, 50%, and 70% are utilized in finite element (FE) models. The crushable foam plasticity model is employed to analyze the scaffolds' mechanical response under quasi-static compression. Experimental validation of the FE results demonstrates a favorable agreement, with an average percentage error of 12.27% ± 7.1%. Moreover, the yield strength and elastic modulus of the scaffolds are evaluated and compared, revealing notable differences between cubic and hexagonal closed-packed designs. The 30%, 50%, and 70% porous cubic pore-shaped bone scaffolds exhibit significantly higher yield strengths of 46.89%, 58.29%, and 66.09%, respectively, compared to the hexagonal closed-packed bone scaffolds at percentage strains of 5%, 6%, and 7%. Similarly, the elastic modulus of the 30%, 50%, and 70% porous cubic pore-shaped bone scaffolds is 42.68%, 59.70%, and 58.18% higher, respectively, than the hexagonal closed-packed bone scaffolds at the same percentage strain levels. Furthermore, it is observed in comparison with our previous study the μSLA-printed bone scaffolds demonstrate 1.5 times higher elastic moduli and yield strengths compared to the PJ-printed bone scaffolds.

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