Abstract
BACKGROUND: Research on atrial fibrillation (AF) and frailty has increasingly attracted scholarly and clinical attention in recent years, driven by the need to understand their complex interactions and improve care for vulnerable populations. This study aims to systematically analyze the evolving landscape of AF (frailty research). METHODS: We extracted data from the Web of Science Core Collection, identifying 687 relevant articles published between 2001 and 2024. Employing bibliometric tools (VOSviewer and CiteSpace), we mapped knowledge networks, analyzing publication trends, contributor geography (46 countries/regions), institutional involvement (1540 institutions), and researcher collaboration (4096 researchers). RESULTS: Publication Trends: Growth Trajectory: Consistent growth in AF-frailty (related publications over the 2001 to 2024 period. Geographic & Institutional Contributions: The United States led in research output, with global participation across 46 countries/regions and 1540 institutions). CONCLUSIONS: AF (frailty research has matured into a multidisciplinary field with expanding global contributions). Future advancements require intensified multidisciplinary collaboration and integration of precision medicine frameworks. Prioritizing these will enable optimized, personalized care for frail AF patients, addressing unmet clinical needs in this high-risk population.