Anterior abdominal wall agenesis associated with cardiac exstrophy and macrocephaly in a gold mining area of the Democratic Republic of the Congo: management and prognosis in a resource-limited area

刚果民主共和国金矿区前腹壁发育不全合并心脏外翻和巨头畸形:资源匮乏地区的治疗和预后

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Abstract

BACKGROUND: Congenital malformations, which are responsible for thousands of neonatal deaths every year, are prevalent in low-resource countries. Severe birth defects are mainly multifactorial but their occurrence may be exacerbated by low socioeconomic conditions and environmental factors, especially in mining areas. CASE PRESENTATION: A male neonate delivered, at term, by caesarean section from a 23-year-old woman presented multiple malformations (cardiac exstrophy, abdominal agenesis) and died 12 h after birth. The (non-consanguineous) father was an artisanal gold miner. No genetic or further morphological testing was done due to lack of resources. DISCUSSION AND CONCLUSION: The present case of severe congenital malformation in a gold mining area of the Democratic Republic of Congo, illustrates the challenges associated with the lack of specialized antenatal and neonatal care in a resource-poor country.

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