Abstract
GIST or gastrointestinal stromal tumors are the most common mesenchymal tumors of the GI tract showing mostly positive c-kit (CD-117) in immuno-histochemical staining. Most of the times, early diagnosis is missed. Usually, patients present with anemia. Sometimes, the patient can present in emergency with massive GI bleed or intestinal obstruction. The aim of this paper was to make the clinicians aware about the varied presentations of GIST. Presenting herewith is our single-center experience of management of patients of GIST with review of the available literature.