Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study

卵巢交界性布伦纳瘤:一例免疫组织化学和分子生物学研究报告

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Abstract

BACKGROUND: Borderline Brenner tumor of the ovary is a rare entity characterized by papillary structures with a fibro-vascular core, covered by a transitional epithelium, and by the absence of stromal infiltration. It is associated, by definition, with a benign component of Brenner tumor. CASE: We report a case of a 68-year-old woman, with a right ovarian mass, whose morphology and immuno-profile were consistent with the diagnosis of a borderline Brenner tumor. Immunohistochemistry carried out on selected markers may help to formulate the diagnosis, more than the molecular analyses.

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