Abstract
Plasma cell dyscrasia is the term used to describe the disorders characterized by neoplastic proliferations of plasma cells with production of immuno globulins. Of all the plasma cell dyscrasias, multiple myeloma is the commonest and clinically important. Multiple myeloma accounts for 1% of all malignancies and 10-20% of all hematologic malignancies. Mostly the patients present with bone pain, pathological fractures, renal insufficiency or infections. Here we present two cases of multiple myeloma with unusual presentations admitted in the otorhinolaryngology department of a tertiary care center. One 50-year old male presented with a mass in the left external auditory canal along with left facial palsy and the other a 45 yr old female, who presented with painful deglutition, multiple mucosal erosion in oral cavity, throat tightness and left side facial pain. Both cases are examined and evaluated and found to have multiple myeloma. They were referred to the Hematology department for further management.