Abstract
BACKGROUND: Adequate sleep is a crucial aspect of overall health. While existing research has highlighted the impact of factors like obesity and lipid profiles on sleep patterns, limited attention has been given to exploring the relationship between sleep duration with novel anthropometric and atherogenic indices. METHODS: This study was part of the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) cohort study. 7,449 participants' sleep duration was assessed at baseline using a questionnaire, and they were followed for 10 years to calculate novel anthropometric and atherogenic indices. RESULTS: Participants who slept over 9 h had a 41.7% higher likelihood of reduced body shape index (ABSI) (ABSI < 0.086, OR: 1.417, P = 0.021) and a 49.5% greater chance of a lower weight-adjusted-waist index (WWI) (WWI < 12, OR: 1.495, P = 0.011). In contrast, less than 6 h of sleep was associated with a 40.1% decrease in the odds of reduced ABSI (OR: 0.599, P < 0.001) and a 32.7% lower likelihood of reduced WWI (OR: 0.673, P < 0.001). Long sleepers also had a 31.3% lower chance of body adiposity index (BAI) < 37.5 (OR: 0.687, P = 0.027) and a 27% reduced chance of high-density lipoprotein (HDL) < 55 mg/dl (OR: 0.730, P = 0.037). Shortened sleep decreased the odds of a lower abdominal volume index (AVI) (AVI < 21) by 19.1% (OR: 0.809, P = 0.010). CONCLUSION: Longer sleep durations were associated with lower ABSI and WWI, while shorter sleep durations correlated with increased ABSI, WWI, and AVI. Additionally, extended sleep was associated with elevated HDL levels, although it also contributed to increased BAI.