Added Sugar Intake from Infant Formula and Complementary Foods: A Longitudinal Investigation and Implications for Infant Weight Gain

婴儿配方奶粉和辅食中添加糖的摄入量:一项纵向研究及其对婴儿体重增加的影响

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Abstract

BACKGROUND: Infant formula contains added sugar, although national recommendations are that added sugar should be avoided for infants. OBJECTIVES: This study aims to estimate average daily added sugar intake from formula and complementary foods and examine associations between added sugar intake from formula and complementary foods and weight status among infants in low-income households. METHODS: Between August 2019 and November 2021, mother-infant dyads were recruited from a pediatric clinic primarily serving Medicaid recipients, regardless of feeding type. 24-h feeding recalls were conducted on infants aged 6, 9, and 12 mo. For directly breast-fed infants, we used the average expected milk volume intake by age. Weight-for-age and weight-for-length z-scores were calculated from health record measurements. Descriptives, bivariate tests, and multilevel linear growth modeling were used. RESULTS: Most participants (n = 234) were African American (39%) or Latino (38%). Infants' daily added sugar intake was on average 7 g from complementary foods and 33 g from formula, with formula being the major source at 6 and 9 mo. Daily intake of calories due to added sugar was significantly higher among formula-fed infants compared with breast milk or sugar-free formula-fed infants (P = 0.034). For every 10 g of added sugar from formula daily, infants' weight-for-length z-scores increased by an average of 0.060 (SE = 0.018, P = 0.001). CONCLUSIONS: Formula significantly contributes to added sugar intake among infants compared with complementary foods. A significant positive association between added sugar from formula and infant weight gain suggests the need for regulations limiting added sugar in formula and including added sugar information on formula food labels.

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