Abstract
Approximately one-third of patients who present for oral immunotherapy (OIT) will be allergic to more than one food. Those patients with more than one food allergy have the option of sequential courses of single-food OIT or, in the right situation, combining several foods as part of multifood OIT. The time and cost savings can be substantial. Treatment protocols used with multiple foods are basically the same as with single-food courses, so clinics proficient with single-food OIT can easily transition to multifood OIT. Outcomes have been shown to be similar between the two approaches, so patients should be offered the opportunity to address their food allergies in one, more convenient OIT course.