[Vocal fold superficial layer of lamina propria histology after the position of mucosa pediculated flap: canine experimental study]

[黏膜蒂瓣置入后声带固有层浅层组织学变化:犬类实验研究]

阅读:1

Abstract

Many techniques were applied to treat patients with sulcus vocalis and scarred vocal folds. Their results were not good enough. In the Technique of Vocal Fold Pediculated Mucosa Flap, an anterior pediculated flap of vocal fold is positioned on the superficial layer of the lamina propria, below the free margin. Aim: To describe histological postoperative findings on the superficial layer of lamina propria during the application of the technique Vocal Fold Pediculated Mucosa Flap. The following parameters were compared between tested and control groups: total, type I and type III collagen and number of cellular nucleus. Study design: experimental. Material and Method: Fifteen dogs were used. One vocal fold was submitted to the intervention and the other was left as control. Each group of three dogs was sacrificed on 10, 30, 90, 180 and 360 days after the experimental surgery. Hematoxylin and eosin (H.E.) and Syrius Red were the staining techniques used. Results: Type I and total collagen suggested increased results in the tested group on postoperative days 90 and 180, nevertheless there was statistical significance only on postoperative day 180 (p<0.05). Type III collagen group area was less significant than the control group on postoperative day 180 (p<0.05). The number of cellular nucleus was increased on the 10th postoperative day, but decreased after the 30th day. Discussion: The findings about total and type I collagen and the amount of cellular nucleus on the superficial layer of lamina propria were similar to laryngeal postoperative studies in dogs. More complex studies would contribute with new data about the present subject.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。