A female with solitary fibrous tumor pleura mimicking pulmonary sclerosing pneumocytoma in low resource setting: A case report

一例资源匮乏地区女性孤立性纤维瘤性胸膜肿瘤,临床表现酷似肺硬化性肺细胞瘤:病例报告

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Abstract

BACKGROUND: Solitary fibrous tumor of pleura (SFTP) is a rare condition. Clinical symptoms and non-specific radiological features in both tumors make preoperative diagnosis difficult to establish. CASE PRESENTATION: A Javanese 47-year-old female complained of chest pain and shortness of breath which an X-ray and CT-Scan of the thorax showed giant cell metastases in the lung. Signs and symptoms indicate pulmonary sclerosing pneumocytoma (PSP) and the patient underwent thoracic surgery which was first performed with angiographic embolization. Furthermore, an anatomical pathology analysis was performed with suspected SFTP, supported by the IHC test, which found CD34 (+), EMA (-), and S100 (-). Thoracic surgery followed by radiotherapy and chemotherapy is recommended in SFTP patients. DISCUSSION: The SFTP and PSP have non-specific clinical symptoms and radiological features. Anatomic pathology and IHC test are definitive diagnostic tools from SFTP and PSP. Establishing a preoperative diagnosis of SFTP and PSP is quite difficult. Surgical resection is the treatment of choice for both. CONCLUSION: The comparison of SFTP and PSP can be seen results of the anatomical pathology analysis and IHC test.

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